Dual-energy CT for therapy monitoring: histogram analyses of iodine maps reveal typical pattern of enhancement
نویسندگان
چکیده
Aim Functional information for appropriate therapy monitoring of advanced targeted therapies is essential, but standard follow up (FU) examinations with computed tomography (CT) still focus on traditional size measurements. Iodine quantification with dual energy CT (DECT) enables additional quantitative assessment of contrast media uptake. Our purpose was to investigate patterns of contrast media enhancement under BRAF inhibitor therapy (BRAF-I) by performing histogram analyses (HA) of iodine maps based on DECT.
منابع مشابه
Dual-energy CT characteristics of colon and rectal cancer allows differentiation from stool by dual-source CT.
PURPOSE We aimed to determine dual-energy computed tomography (DECT) characteristics of colorectal cancer and investigate effectiveness of DECT method in differentiating tumor from stool in patients with colorectal cancer. METHODS Fifty consecutive patients with colorectal tumors were enrolled. Staging was performed by DECT (80-140 kV) using dual-source CT after rectal air insufflation and wi...
متن کاملComparing 511 keV Attenuation Maps Obtained from Different Energy Mapping Methods for CT Based Attenuation Correction of PET Data
Introduction: The advent of dual-modality PET/CT scanners has revolutionized clinical oncology by improving lesion localization and facilitating treatment planning for radiotherapy. In addition, the use of CT images for CT-based attenuation correction (CTAC) decreases the overall scanning time and creates a noise-free attenuation map (6map). CTAC methods include scaling, s...
متن کاملClinical utility of dual-energy CT in the evaluation of solitary pulmonary nodules: initial experience.
PURPOSE To determine the clinical utility of dual-energy computed tomography (CT) in evaluating solitary pulmonary nodules (SPNs). MATERIALS AND METHODS This study was approved by the institutional review board, and informed consent was obtained. CT scans were obtained before and 3 minutes after contrast material injection in 49 patients (26 men, 23 women; mean age, 60.39 years +/- 12.24 [sta...
متن کاملMultifunctional GQDs-Coated Fe/Bi Nanohybrids for CT/MR Dual Imaging and in vitro Photothermal Therapy
Introduction: The multipurpose nanocomposites have gained growing biomedical attention as promising nanotheranostics to improve The effectiveness of cancer treatment, which concurrently combine advantages of the therapeutic and diagnostic techniques into one nanosystem. The “all-in on” probes not only help to ablate cancerous tumors, but also allow to optimize and monitoring of...
متن کاملDual-Energy CT in Patients Treated with Anti-Angiogenic Agents for Non-Small Cell Lung Cancer: New Method of Monitoring Tumor Response?
OBJECTIVE To evaluate tumor responses in patients treated with anti-angiogenic agents for non-small cell lung cancer (NSCLC) by assessing intratumoral changes using a dual-energy CT (DECT) (based on Choi's criteria) and to compare it to traditional Response Evaluation Criteria in Solid Tumors (RECIST) criteria. MATERIALS AND METHODS Ten NSCLC patients treated with bevacizumab underwent DECT. ...
متن کامل